In 2002 he won the International Brahms Competition in Portschach, Austria. He had already won prizes at many important competitions in his homeland and abroad. Miroslav Sekera began playing piano at the age of three. At the same time, he also began studying violin. He devoted himself to both instruments until his admission to the Prague Conservatoire, where he decided in favour of the piano. He then furthered his studies at the Academy of Performing Arts in Prague. In 2006 he recorded a solo album of works by Brahms, Scarlatti, and Moszkovski. He stands out in his peers for his versatile approach to concert appearances and to daily musical practice. As a soloist and a performer of chamber music, Sekera has appeared on prestigious stages in Vienna, Washington, Tokyo and other cities around the world. He collaborates regularly with Czech Radio and the Prague Symphony Orchestra. Among his regular artistic partners are the violinist Josef Špaček, the mezzo-soprano Dagmar Pecková, and the French horn player Radek Baborák. In 2016 he made his debut in the Dvořák Hall at the Rudolfinum. In 2018 he appeared at the Rudolf Firkušný Piano Festival. In 2019 he gave concerts in Japan with the legendary cellist Tsuyoshi Tsutsumi. In 2020, Supraphon released his solo album with works by Liszt and Smetana, and in 2022 he made with the Prague Radio Symphony Orchestra an album with works by Kabeláč, for which they won the Anděl Award.